No 3 Vera Zvonareva's loss in the fourth round Sunday, following earlier exits by No 1 Caroline Wozniacki and No 2 Kim Clijsters, makes this year's French Open the first in the Open era with none of the top three seeded women in the quarterfinals.
Fourth seed Andy Murray hopes to have recovered from an ankle injury in time to face Serbia's Viktor Troicki in the French Open fourth round on Monday when Rafa Nadal and Maria Sharapova are also in action.
Australian Open finalist Li Na moved into the fourth round of the French Open on Saturday, beating Sorana Cirstea of Romania 6-2, 6-2.
Top-ranked Caroline Wozniacki will have to wait for her first major title after losing to Daniela Hantuchova 6-1, 6-3 Friday in the third round of the French Open.
After wasting two match points in the second set and feeling her confidence fading, Kim Clijsters let the match slip away on Thursday at the French Open.
The world No 7 Li Na of China held off strong challenges from Spanish qualifier Silvia Soler-Espinosa to win the women's singles second round match 6-4 and 7-5 at the French Open on Thursday.
Former world number one Amelie Mauresmo has been barred from playing the French Open mixed doubles because she is not registered in the anti-doping programme, organisers said on Wednesday.
Chinese tennis player Peng Shuai beat Polona Hercog of Slovenia 7-5 6-1, making history to reach her first French Open third round.
Vera Zvonareva was fortunate to progress to the French Open third round with a 4-6 7-5 7-5 victory after German Sabine Lisicki needed a medical time out and then crumbled with victory almost in her grasp on Wednesday.
It's newsworthy enough when anyone manages to win a set against Rafael Nadal at any stage of the French Open - let alone two sets in the first round.
Australian Open finalist Li Na reached the second round of the French Open after beating Barbora Zahlavova Strycova 6-3, 6-7 (6), 6-3 on Tuesday.
Chinese players clinched good start at the French Open as Peng Shuai beat Austria's Tamira Paszek 6-3 6-2 and Zheng Jie beat Sandra Zahlavova of Czech Republic 6-4 6-3 in the first round of the tournament.