Protein inhibitor may help cure liver cancer
By Zhang Yangfei | China Daily | Updated: 2019-03-04 07:25
Chinese scientists have identified a protein that causes the proliferation of liver cancer cells, which could assist in the development of a new cancer drug.
By studying proteins of patients with early-stage liver cancer, researchers found that the activity of one protein, identified as SOAT1, can affect cholesterol stability in cancer cells - which triggers them to proliferate and migrate.
The study also found that avasimibe, an inhibitor of SOAT1, shows potential as a targeted therapeutic drug.
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