100 years on, Spanish Flu carries warning

PARIS - It was the disease to end all others, infecting a third of humanity, killing tens of millions in their beds and prompting panicked talk of the end of days across continents still reeling from war.

One hundred years on from the influenza outbreak known as the Spanish Flu, scientists say that while lessons have been learned from the deadliest pandemic in history, the world is ill-prepared for the next global killer.

In particular, they warn that shifting demographics, antibiotic resistance and climate change could all complicate any future outbreak.