$850k: Price tag on gene therapy for rare form of blindness

WASHINGTON - A first-of-its-kind genetic treatment for blindness will cost $850,000 per patient, making it one of the most expensive medicines in the world and raising questions about the affordability of a coming wave of similar gene-targeting therapies.

The injectable treatment from Spark Therapeutics can improve the eyesight of patients with a rare genetic mutation that affects just a few thousand people in the United States. Previously, there has been no treatment for the condition, which eventually causes complete blindness by adulthood.

Pricing questions have swirled around the treatment due to a number of unusual factors: it is intended to be a onetime treatment, it treats a very small number of patients and represents a medical breakthrough.