MOSCOW - At least five people, including two children, were killed and 18 others injured when a bus collided with a truck in Russia's Novosibirsk region early Sunday, the RIA Novosti news agency quoted local emergencies ministry as saying.

The bus, carrying 35 or 38 people, rammed into a heavy duty Kamaz truck at about 2 am local time (1900 GTM Saturday), said a spokesman of the ministry.

Ten people have been sent to hospital with six seriously injured. Police had started investigation into the accident.

The bus, traveling from Kazakhstan's Semipalatinsk to Russia's Tomsk, went in the wrong direction when the collision happened.