India now has the largest number of AIDS infections as the spread of the disease shows no sign of letting up a quarter-century into an epidemic that has claimed 25 million lives, the U.N. reported Tuesday.

Actress Naomi Watts, and Mary Fisher, right, both special representatives to the United Nations' program for HIV/AIDS join Peter Piot, center, executive director of the program and United Nations employees, special representatives, tourists and others who took part in an event creating a human red ribbon formed by people holding red umbrellas to symbolize the fight against HIV/AIDS on the North Garden at United Nations headquarters Tuesday, May, 30, 2006. Fisher is HIV-positive and an anti-AIDS activist. [AP]

"I think we will see a further globalization of the epidemic spreading to every single corner of the planet,"

UNAIDS head Dr. Peter Piot told The Associated Press in an interview.

The data released by UNAIDS shows that India now has the largest number of people living with HIV/AIDS. With an estimated 5.7 million infections, it has surpassed South Africa's 5.5 million.

But the epidemic still remains at its worst in sub-Saharan Africa, where per capita rates continue to climb in several countries. A third of adults were infected in Swaziland in 2005. By comparison, India's per capita rate is low, at 0.9 percent of its 1.02 billion people.

The 630-page UNAIDS report released Tuesday documents countries' progress and failures, and projects what must happen to keep some regions from experiencing disaster. The agency report was released a day ahead of a high-level meeting on AIDS in New York, and a week prior to the 25th anniversary of the first documented AIDS cases on June 5, 1981.

Nearly 40 million people are living with HIV/AIDS.

"It won't go away one fine day, and then we wake up and say, 'Oh, AIDS is gone,'" Piot told the AP in a recent telephone interview from Geneva.

He said one of the report's most disturbing findings was how few babies are being protected against infection. Only 9 percent of pregnant women in poor countries are receiving services, such as access to drugs, to help prevent mother-to-child transmission, despite a UNAIDS goal of 80 percent coverage.

"The thing I'm most disappointed with and surprised about is prevention of mother-to-child transmission," Piot said. "For HIV, the coverage is still very low and we didn't meet the target. "Here we have something that is non-controversial; it's about saving the babies."

Women's vulnerability to the disease continues to increase, with more than 17 million women infected worldwide, nearly half the global total and more than three-quarters of them living in sub-Saharan Africa, the report found.

Stigma and discrimination still plague those infected worldwide, and young people's knowledge about HIV/AIDS remains low with less than 50 percent having adequate information about the disease, a far cry from the 90 percent target UNAIDS set for 2005.

Piot said the situation in sub-Saharan Africa remains dismal, where 24.5 million people were infected and home to nearly 90 percent of the world's children living with the virus.

South Africa remains one of the world's most tragic situations with nearly one in three pregnant women testing HIV-positive in public antenatal clinics in 2004. Nearly 19 percent of adults were infected nationwide last year, and the per capita rate is continuing to climb.

"I think in Africa, it is only comparable in demographic terms to the slave trade regarding the impact it has had on the population," Piot said. "In southern Africa, HIV prevalence continues to go up, and they're already the world record."

But Piot said the new numbers do offer a small sliver of hope. Kenya and Zimbabwe, along with some cities in Burkina Faso, reported declines in the overall percentage of adults infected. He said Thailand and Uganda were two of the only previous examples where epidemics were curbed.

In India, officials said there are signs of hope despite the huge number of infections.

Intensive AIDS prevention efforts among prostitutes and the men who frequent them have pushed down HIV infections dramatically in four south Indian states, Andhra Pradesh, Karnataka, Maharashtra and Tamil Nadu. The UNAIDS report said the decline in HIV prevalence in those states was in 15- to 24-year-old pregnant women, where the rate fell from 1.7 percent in 2001 to 1.1 percent in 2004.

A recent University of Toronto study in those states credited efforts by authorities and non-governmental groups to educate sex workers. Places like Kamathipura are now scattered with posters and street theater performances and educators, all sharing information about AIDS and HIV. Bombay is in Maharashtra state.

Piot, at a news conference in New York on Tuesday, said that while four Indian states had been investing in HIV prevention, "the rest of the country is a totally different situation. There is an increase in new infections."

"With a huge country like India, what matters is basically work in each and every state," he said.

The Asia-Pacific region, with 8.3 million people infected, is the second-highest after sub-Saharan Africa.

Piot, in the AP interview, said that the sheer population of Asia, home to most of the world's population, makes it a potential problem because even small gains in per capita infections equal huge numbers, especially in countries like China and India, with over 1 billion people each.

He said Eastern Europe and Central Asia have become a new front where infections have expanded as people have access to more money and started buying injecting drugs instead of just shipping them through from countries like Afghanistan.

"Absolute numbers are still low, but when you look at the spread of the disease, we know from experience where that leads," Piot said. "The Middle East is the last part of the world where HIV is not spreading rapidly."

Thoraya Ahmed Obeid, executive director of the U.N. Fund for Population Activities, stressed that more action must be taken to empower women and enable them to take control of their sexuality. This is particularly important in southern Africa where sexual violence against women is a factor in the transmission of HIV.

Piot said that there is time to stop AIDS from worsening, but action is needed on a number of fronts. Currently, about 1.3 million people in poor countries have access to antiretroviral treatment, but about 80 percent still are not receiving drugs.

"Intervention is very low ... for many critical populations in many countries. We need to really intensify the response to AIDS," Piot said.