"She wants to step up her action in what she calls Red Alert areas, the most seriously troubled, war-torn areas in the world.
"She's in talks to go into Burma and help with students and AIDS victims who are suffering terribly."
Mum and Dad: Angelina and Brad's daughter, Shiloh, shares a buggy with Zahara
The source added Angelina had been talking to a monk about a safe travel route through the military state and a visit to an orphanage.
She is said to believe adopting another girl would balance her family and a child from Burma would fit into its racial mix.
Angelina has enlisted the help of Dr Jane Aronson, an adoption specialist who runs the Worldwide Orphans Foundation.
It is understood she has acted as a mentor to the actress after helping her with the adoption of Zahara.