Jennifer Aniston and Vince Vaughn

Jennifer Aniston and Vince Vaughn have split, just two months after the release of their romantic comedy, The Break-Up.

The Hollywood golden girl is reported to have called off her engagement to Vaughn after speculation the pair was heading for separation.

Aniston and Vaughn arrived separately to the Sydney premiere of the film.

The actress is reportedly single again and is calling on best friends Courteney Cox Arquette, Sheryl Crow and volleyball star Gabrielle Reece to help her cope with another broken romance.

Reports of the split come amid a series of magazine articles which said Aniston was not yet over her ex, Brad Pitt.

American NW magazine reported Aniston initiated the split because she did not believe Vaughn was the "marrying kind".

But Hollywood sources claimed Vaughn's mother told him he would be in for "a world of heartbreak" if he married Aniston because she had "not found closure" with her ex-husband.

Aniston staged a girls-only get together at Cox Arquette's Malibu home July 24 and has been referring to herself as ''the new Jen'' ever since.

Aniston and Vaughn -- who starred together in this year's anti-relationship comedy The Break-Up -- never officially announced their engagement, but tabloids were rife with wedding plans.

Pitt walked out on Aniston after falling in love with Hollywood temptress Angelina Jolie, who recently gave birth to their daughter, Shiloh, in Namibia, Africa.

US media had claimed Aniston wanted the role for herself.